TRPM4 regulates Akt/GSK3‐β activity and enhances β‐catenin signaling and cell proliferation in prostate cancer cells

Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing TRPM4 levels leads to the reduced proliferation of PC3 cells. This effect was...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Sagredo, Alfredo I., Sagredo, Eduardo A., Cappelli, Claudio, Báez, Pablo, Andaur, Rodrigo E., Blanco, Constanza, Tapia, Julio C., Echeverría, César, Cerda, Oscar, Stutzin, Andrés, Simon, Felipe, Marcelain, Katherine, Armisén, Ricardo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792731/
https://ncbi.nlm.nih.gov/pubmed/28614631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12100
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