TRPM4 regulates Akt/GSK3‐β activity and enhances β‐catenin signaling and cell proliferation in prostate cancer cells

Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing TRPM4 levels leads to the reduced proliferation of PC3 cells. This effect was...

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Bibliografische gegevens
Gepubliceerd in:Mol Oncol
Hoofdauteurs: Sagredo, Alfredo I., Sagredo, Eduardo A., Cappelli, Claudio, Báez, Pablo, Andaur, Rodrigo E., Blanco, Constanza, Tapia, Julio C., Echeverría, César, Cerda, Oscar, Stutzin, Andrés, Simon, Felipe, Marcelain, Katherine, Armisén, Ricardo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792731/
https://ncbi.nlm.nih.gov/pubmed/28614631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12100
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