Immunotherapy for Infarcts: In Vivo Postinfarction Macrophage Modulation Using Intramyocardial Microparticle Delivery of Map4k4 Small Interfering RNA

The myeloid cells infiltrating the heart early after acute myocardial infarction elaborate a secretome that largely orchestrates subsequent ventricular wall repair. Regulating this innate immune response could be a means to improve infarct healing. To pilot this concept, we utilized (β1,3-d-) glucan...

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Detalhes bibliográficos
Publicado no:Biores Open Access
Main Authors: Luo, Jun, Weaver, Matthew S., Fitzgibbons, Timothy P., Aouadi, Myriam, Czech, Michael P., Allen, Margaret D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757732/
https://ncbi.nlm.nih.gov/pubmed/33376632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2020.0037
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