One-Step Homology Mediated CRISPR-Cas Editing in Zygotes for Generating Genome Edited Cattle

Selective breeding and genetic modification have been the cornerstone of animal agriculture. However, the current strategy of breeding animals over multiple generations to introgress novel alleles is not practical in addressing global challenges such as climate change, pandemics, and the predicted n...

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Vydáno v:CRISPR J
Hlavní autoři: Park, Ki-Eun, Frey, Juli Foster, Waters, Jerel, Simpson, Sean G., Coutu, Chris, Plummer, Sarah, Campbell, Matthew, Donovan, David M., Telugu, Bhanu P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2020
Témata:
Research Articles: Expanding the CRISPR Toolbox
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757693/
https://ncbi.nlm.nih.gov/pubmed/33252243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2020.0047
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