TLR4 Response to LPS Is Reinforced by Urokinase Receptor

GPI-anchored uPAR is the receptor for the extracellular serine protease urokinase-type plasminogen activator (uPA). Though uPAR role in inflammatory processes is documented, underlying mechanisms are not fully understood. In this study we demonstrate that uPAR is a part of Toll-like receptor 4 (TLR4...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Kiyan, Yulia, Tkachuk, Sergey, Rong, Song, Gorrasi, Anna, Ragno, Pia, Dumler, Inna, Haller, Hermann, Shushakova, Nelli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757075/
https://ncbi.nlm.nih.gov/pubmed/33362762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.573550
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