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CAFs affect the proliferation and treatment response of head and neck cancer spheroids during co-culturing in a unique in vitro model

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors for which the overall survival rate worldwide is around 60%. The tumor microenvironment, including cancer-associated fibroblasts (CAFs), is believed to affect the treatment response and migration of HNSCC. T...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Magan, Mustafa, Wiechec, Emilia, Roberg, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756959/
https://ncbi.nlm.nih.gov/pubmed/33353547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01718-6
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