Full-length and C-terminal neurogranin in Alzheimer’s disease cerebrospinal fluid analyzed by novel ultrasensitive immunoassays

BACKGROUND: Neurogranin (Ng) is a neuron-specific and postsynaptic protein that is abundantly expressed in the brain, particularly in the dendritic spine of the hippocampus and cerebral cortex. The enzymatic cleavage of Ng produces fragments that are released into cerebrospinal (CSF), which have bee...

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Vydáno v:Alzheimers Res Ther
Hlavní autoři: Öhrfelt, Annika, Dumurgier, Julien, Zetterberg, Henrik, Vrillon, Agathe, Ashton, Nicholas J., Kvartsberg, Hlin, Bouaziz-Amar, Elodie, Hugon, Jacques, Paquet, Claire, Blennow, Kaj
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756958/
https://ncbi.nlm.nih.gov/pubmed/33353563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00748-6
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