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The Impact of Halogenated Phenylalanine Derivatives on NFGAIL Amyloid Formation

The hexapeptide hIAPP(22–27) (NFGAIL) is known as a crucial amyloid core sequence of the human islet amyloid polypeptide (hIAPP) whose aggregates can be used to better understand the wild‐type hIAPP′s toxicity to β‐cell death. In amyloid research, the role of hydrophobic and aromatic‐aromatic intera...

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Vydáno v:Chembiochem
Hlavní autoři: Chowdhary, Suvrat, Moschner, Johann, Mikolajczak, Dorian J., Becker, Maximilian, Thünemann, Andreas F., Kästner, Claudia, Klemczak, Damian, Stegemann, Anne‐Katrin, Böttcher, Christoph, Metrangolo, Pierangelo, Netz, Roland R., Koksch, Beate
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756607/
https://ncbi.nlm.nih.gov/pubmed/33405360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000373
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