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Aptamer‐Mediated Reversible Transactivation of Gene Expression by Light

The investigation and manipulation of cellular processes with subcellular resolution requires non‐invasive tools with spatiotemporal precision and reversibility. Building on the interaction of the photoreceptor PAL with an RNA aptamer, we describe a variation of the CRISPR/dCAS9 system for light‐con...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Renzl, Christian, Kakoti, Ankana, Mayer, Günter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756287/
https://ncbi.nlm.nih.gov/pubmed/32865316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202009240
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