Pharmacodynamic monitoring of factor VIII replacement therapy in hemophilia A: Combining thrombin and plasmin generation

BACKGROUND: Clinical severity of hemophilia A (HA) varies, possibly due to interplay of many factors in the hemostatic pathway. Pharmacokinetic monitoring of factor VIII (FVIII) replacement therapy in HA patients consists of measuring FVIII activity levels and subsequent dose adjustment. The Nijmege...

詳細記述

保存先:
書誌詳細
出版年:J Thromb Haemost
主要な著者: Valke, Lars L.F.G., Bukkems, Laura H., Barteling, Wideke, Laros‐van Gorkom, Britta A.P., Blijlevens, Nicole M.A., Mathôt, Ron A.A., van Heerde, Waander L., Schols, Saskia E.M.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
HAEMOSTASIS
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756259/
https://ncbi.nlm.nih.gov/pubmed/32979031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15106
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