Proteome profiling and vector yield optimization in a recombinant adeno‐associated virus‐producing yeast model

Recent studies on recombinant adeno‐associated viral (rAAV) vector production demonstrated the generation of infectious viral particles in Saccharomyces cerevisiae. Proof‐of‐concept results showed low vector yields that correlated with low AAV DNA encapsidation rates. In an attempt to understand the...

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Publicado en:Microbiologyopen
Autores principales: Aponte‐Ubillus, Juan Jose, Barajas, Daniel, Sterling, Harry, Aghajanirefah, Ali, Bardliving, Cameron, Peltier, Joseph, Shamlou, Parviz, Roy, Mimi, Gold, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755776/
https://ncbi.nlm.nih.gov/pubmed/33166081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.1136
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