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Proteome profiling and vector yield optimization in a recombinant adeno‐associated virus‐producing yeast model

Recent studies on recombinant adeno‐associated viral (rAAV) vector production demonstrated the generation of infectious viral particles in Saccharomyces cerevisiae. Proof‐of‐concept results showed low vector yields that correlated with low AAV DNA encapsidation rates. In an attempt to understand the...

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Detalhes bibliográficos
Publicado no:Microbiologyopen
Main Authors: Aponte‐Ubillus, Juan Jose, Barajas, Daniel, Sterling, Harry, Aghajanirefah, Ali, Bardliving, Cameron, Peltier, Joseph, Shamlou, Parviz, Roy, Mimi, Gold, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755776/
https://ncbi.nlm.nih.gov/pubmed/33166081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.1136
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