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Proteome profiling and vector yield optimization in a recombinant adeno‐associated virus‐producing yeast model

Recent studies on recombinant adeno‐associated viral (rAAV) vector production demonstrated the generation of infectious viral particles in Saccharomyces cerevisiae. Proof‐of‐concept results showed low vector yields that correlated with low AAV DNA encapsidation rates. In an attempt to understand the...

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Библиографические подробности
Опубликовано в: :Microbiologyopen
Главные авторы: Aponte‐Ubillus, Juan Jose, Barajas, Daniel, Sterling, Harry, Aghajanirefah, Ali, Bardliving, Cameron, Peltier, Joseph, Shamlou, Parviz, Roy, Mimi, Gold, Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755776/
https://ncbi.nlm.nih.gov/pubmed/33166081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.1136
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