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Computational fluid dynamic modeling of alternating tangential flow filtration for perfusion cell culture

Alternating tangential flow (ATF) filtration has been successfully adopted as a low shear cell separation device in many perfusion‐based processes. The reverse flow per cycle is used to minimize fouling compared with tangential flow filtration. Currently, modeling of the ATF system is based on empir...

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Dettagli Bibliografici
Pubblicato in:Biotechnol Bioeng
Autori principali: Radoniqi, Flaka, Zhang, Hu, Bardliving, Cameron L., Shamlou, Parviz, Coffman, Jon
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221016/
https://ncbi.nlm.nih.gov/pubmed/30080936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26813
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