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Aryl Sulfonium Salts for Site‐Selective Late‐Stage Trifluoromethylation

Incorporation of the CF(3) group into arenes has found increasing importance in drug discovery. Herein, we report the first photoredox‐catalyzed cross‐coupling of aryl thianthrenium salts with a copper‐based trifluoromethyl reagent, which enables a site‐selective late‐stage trifluoromethylation of a...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Ye, Fei, Berger, Florian, Jia, Hao, Ford, Joseph, Wortman, Alan, Börgel, Jonas, Genicot, Christophe, Ritter, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754511/
https://ncbi.nlm.nih.gov/pubmed/31389649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906672
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