SynGAP splice variants display heterogeneous spatio‐temporal expression and subcellular distribution in the developing mammalian brain

The SynGAP protein is a major regulator of synapse biology and neural circuit function. Genetic variants linked to epilepsy and intellectual disability disrupt synaptic function and neural excitability. SynGAP has been involved in multiple signaling pathways and can regulate small GTPases with very...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Gou, Gemma, Roca‐Fernandez, Adriana, Kilinc, Murat, Serrano, Elena, Reig‐Viader, Rita, Araki, Yoichi, Huganir, Richard L., de Quintana‐Schmidt, Cristian, Rumbaugh, Gavin, Bayés, Àlex
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754318/
https://ncbi.nlm.nih.gov/pubmed/32068252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14988
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