Aloe emodin relieves Ang II‐induced endothelial junction dysfunction via promoting ubiquitination mediated NLRP3 inflammasome inactivation

Recent studies have revealed that aloe emodin (AE), a natural compound from the root and rhizome of Rheum palmatum L., exhibits significant pharmacologic activities. However, the pharmacologic relevance of the compound, particularly for cardiovascular disease, remains largely unknown. Here, we hypot...

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Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: Zhang, Yi, Song, Ziqing, Huang, Shan, Zhu, Li, Liu, Tianyi, Shu, Hongyan, Wang, Lei, Huang, Yi, Chen, Yang
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Inflammation, Extracellular Mediators, & Effector Molecules
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754316/
https://ncbi.nlm.nih.gov/pubmed/32573820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3MA0520-582R
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