Aloe emodin relieves Ang II‐induced endothelial junction dysfunction via promoting ubiquitination mediated NLRP3 inflammasome inactivation

Recent studies have revealed that aloe emodin (AE), a natural compound from the root and rhizome of Rheum palmatum L., exhibits significant pharmacologic activities. However, the pharmacologic relevance of the compound, particularly for cardiovascular disease, remains largely unknown. Here, we hypot...

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Detalles Bibliográficos
Publicado en:J Leukoc Biol
Main Authors: Zhang, Yi, Song, Ziqing, Huang, Shan, Zhu, Li, Liu, Tianyi, Shu, Hongyan, Wang, Lei, Huang, Yi, Chen, Yang
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754316/
https://ncbi.nlm.nih.gov/pubmed/32573820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3MA0520-582R
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