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Primary Sulfonamide Synthesis Using the Sulfinylamine Reagent N-Sulfinyl-O-(tert-butyl)hydroxylamine, t-BuONSO

[Image: see text] Sulfonamides have played a defining role in the history of drug development and continue to be prevalent today. In particular, primary sulfonamides are common in marketed drugs. Here we describe the direct synthesis of these valuable compounds from organometallic reagents and a nov...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Davies, Thomas Q., Tilby, Michael J., Skolc, David, Hall, Adrian, Willis, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754190/
https://ncbi.nlm.nih.gov/pubmed/33237777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c03505
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