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Docosahexaenoic acid protection against palmitic acid‐induced lipotoxicity in NGF‐differentiated PC12 cells involves enhancement of autophagy and inhibition of apoptosis and necroptosis

Lipotoxicity (LTx) leads to cellular dysfunction and cell death and has been proposed to be an underlying process during traumatic and hypoxic injuries and neurodegenerative conditions in the nervous system. This study examines cellular mechanisms responsible for docosahexaenoic acid (DHA 22:6 n‐3)...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Montero, Manuel L., Liu, Jo‐Wen, Orozco, José, Casiano, Carlos A., De Leon, Marino
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754135/
https://ncbi.nlm.nih.gov/pubmed/32379343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15038
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