Loganetin and 5‐fluorouracil synergistically inhibit the carcinogenesis of gastric cancer cells via down‐regulation of the Wnt/β‐catenin pathway

Although most gastrointestinal tumours are sensitive to 5‐fluorouracil (5FU), drug resistance is commonly occurred after 5FU therapy in gastric cancer (GC). Loganetin is the primary active compound in Cornus officinali. However, the synergetic effects of loganetin and 5FU on GC remain unknown. Here,...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Zhou, Huaixiang, Hu, Xiaoge, Li, Na, Li, Guangyan, Sun, Xiaotian, Ge, Feimin, Jiang, Jiahong, Yao, Jingchun, Huang, Dongsheng, Yang, Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754039/
https://ncbi.nlm.nih.gov/pubmed/33098378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15932
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