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Loganetin and 5‐fluorouracil synergistically inhibit the carcinogenesis of gastric cancer cells via down‐regulation of the Wnt/β‐catenin pathway

Although most gastrointestinal tumours are sensitive to 5‐fluorouracil (5FU), drug resistance is commonly occurred after 5FU therapy in gastric cancer (GC). Loganetin is the primary active compound in Cornus officinali. However, the synergetic effects of loganetin and 5FU on GC remain unknown. Here,...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhou, Huaixiang, Hu, Xiaoge, Li, Na, Li, Guangyan, Sun, Xiaotian, Ge, Feimin, Jiang, Jiahong, Yao, Jingchun, Huang, Dongsheng, Yang, Liu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754039/
https://ncbi.nlm.nih.gov/pubmed/33098378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15932
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