Reversal of Cancer Multidrug Resistance (MDR) Mediated by ATP-Binding Cassette Transporter G2 (ABCG2) by AZ-628, a RAF Kinase Inhibitor

Overexpression of ABCG2 remains a major impediment to successful cancer treatment, because ABCG2 functions as an efflux pump of chemotherapeutic agents and causes clinical multidrug resistance (MDR). Therefore, it is important to uncover effective modulators to circumvent ABCG2-mediated MDR in cance...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Cell Dev Biol
Egile Nagusiak: Wang, Jing-Quan, Teng, Qiu-Xu, Lei, Zi-Ning, Ji, Ning, Cui, Qingbin, Fu, Han, Lin, Lizhu, Yang, Dong-Hua, Fan, Ying-Fang, Chen, Zhe-Sheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2020
Gaiak:
Cell and Developmental Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753047/
https://ncbi.nlm.nih.gov/pubmed/33364237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.601400
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