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Baicalin reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal injury in type 1 diabetic mouse model

Baicalin is a flavone glycoside that possesses numerous pharmacological properties. but its protective mode of action in kidney injury induced by diabetes mellitus remains incompletely understood. Using a streptozotocin (STZ)-induced diabetic mouse model, we found that baicalin could ameliorate diab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Zhang, Xiao-Tan, Wang, Guang, Ye, Liu-Fang, Pu, Yu, Li, Run-Tong, Liang, Jianxin, Wang, Lijun, Lee, Kenneth Ka Ho, Yang, Xuesong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751632/
https://ncbi.nlm.nih.gov/pubmed/33190590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2020.1843815
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