MegaPath: sensitive and rapid pathogen detection using metagenomic NGS data

BACKGROUND: Next-generation sequencing (NGS) enables unbiased detection of pathogens by mapping the sequencing reads of a patient sample to the known reference sequence of bacteria and viruses. However, for a new pathogen without a reference sequence of a close relative, or with a high load of mutat...

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發表在:BMC Genomics
Main Authors: Leung, Chi-Ming, Li, Dinghua, Xin, Yan, Law, Wai-Chun, Zhang, Yifan, Ting, Hing-Fung, Luo, Ruibang, Lam, Tak-Wah
格式: Artigo
語言:Inglês
出版: BioMed Central 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751095/
https://ncbi.nlm.nih.gov/pubmed/33349238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06875-6
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