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Morphine and HIV-1 Tat interact to cause region-specific hyperphosphorylation of tau in transgenic mice

Opiate abuse is prevalent among HIV-infected individuals and may exacerbate HIV-associated age-related neurocognitive disorders. However, the extent to which HIV and opiates converge to accelerate pathological traits indicative of brain aging remains unknown. The pathological phospho-isotypes of tau...

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Pubblicato in:Neurosci Lett
Autori principali: Ohene-Nyako, Michael, Nass, Sara R., Hahn, Yun K., Knapp, Pamela E., Hauser, Kurt F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750279/
https://ncbi.nlm.nih.gov/pubmed/33202259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2020.135502
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