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HIV-1 Tat and Morphine Have Interactive Effects on Oligodendrocyte Survival and Morphology

HIV-infected individuals who abuse opiates show faster progression to AIDS, and enhanced incidence of HIV-1 encephalitis. Most opiates with abuse liability are preferential agonists for μ-opioid receptors (MORs), and MORs are expressed on both neurons and glia, including oligodendrocytes (OLs). Tat,...

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Détails bibliographiques
Auteurs principaux: Hauser, Kurt F., Hahn, Yun Kyung, Adjan, Valeriya V., Zou, Shiping, Buch, Shreya K., Nath, Avindra, Bruce-Keller, Annadora J., Knapp, Pamela E.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743138/
https://ncbi.nlm.nih.gov/pubmed/18756534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20746
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