Preformulation Characterization and the Effect of Ionic Excipients on the Stability of a Novel DB Fusion Protein

Shigella ssp cause bacillary dysentery (shigellosis) which has high global morbidity in young children and the elderly. The virulence of Shigella relies upon a type III secretion system (T3SS) which injects host altering effector proteins into targeted intestinal cells. The Shigella T3SS contains tw...

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Bibliografiset tiedot
Julkaisussa:J Pharm Sci
Päätekijät: Jain, Akshay, Hu, Gang, Ratnakaram, Siva Sai Kumar, Johnson, David K., Picking, William D., Picking, Wendy L., Middaugh, Charles Russell
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750262/
https://ncbi.nlm.nih.gov/pubmed/32916136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2020.09.008
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