Brain metabolites in cholinergic and glutamatergic pathways are altered by pancreatic cancer cachexia

BACKGROUND: Cachexia is a major cause of morbidity in pancreatic ductal adenocarcinoma (PDAC) patients. Our purpose was to understand the impact of PDAC‐induced cachexia on brain metabolism in PDAC xenograft studies, to gain new insights into the causes of cachexia‐induced morbidity. Changes in mous...

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Detalles Bibliográficos
Publicado en:J Cachexia Sarcopenia Muscle
Main Authors: Winnard, Paul T., Bharti, Santosh Kumar, Sharma, Raj Kumar, Krishnamachary, Balaji, Mironchik, Yelena, Penet, Marie‐France, Goggins, Michael G., Maitra, Anirban, Kamel, Ihab, Horton, Karen M., Jacobs, Michael A., Bhujwalla, Zaver M.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749557/
https://ncbi.nlm.nih.gov/pubmed/33006443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12621
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