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Generation and initial characterization of novel tumour organoid models to study human pancreatic cancer‐induced cachexia

BACKGROUND: The majority of patients with pancreatic cancer develops cachexia. The mechanisms underlying cancer cachexia development and progression remain elusive, although tumour‐derived factors are considered to play a major role. Pancreatic tumour organoids are in vitro three‐dimensional organ‐l...

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Détails bibliographiques
Publié dans:J Cachexia Sarcopenia Muscle
Auteurs principaux: Vaes, Rianne D.W., van Dijk, David P.J., Welbers, Tessa T.J., Blok, Marinus J., Aberle, Merel R., Heij, Lara, Boj, Sylvia F., Olde Damink, Steven W.M., Rensen, Sander S.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749546/
https://ncbi.nlm.nih.gov/pubmed/33047901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12627
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