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An engineered 4-1BBL fusion protein with “activity on demand”
Engineered cytokines are gaining importance in cancer therapy, but these products are often limited by toxicity, especially at early time points after intravenous administration. 4-1BB is a member of the tumor necrosis factor receptor superfamily, which has been considered as a target for therapeuti...
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| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749310/ https://ncbi.nlm.nih.gov/pubmed/33239441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013615117 |
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