The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling

Cellular RNA polymerases (RNAPs) can become trapped on DNA or RNA, threatening genome stability and limiting free enzyme pools, but how RNAP recycling into active states is achieved remains elusive. In Bacillus subtilis, the RNAP δ subunit and NTPase HelD have been implicated in RNAP recycling. We s...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Pei, Hao-Hong, Hilal, Tarek, Chen, Zhuo A., Huang, Yong-Heng, Gao, Yuan, Said, Nelly, Loll, Bernhard, Rappsilber, Juri, Belogurov, Georgiy A., Artsimovitch, Irina, Wahl, Markus C.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749165/
https://ncbi.nlm.nih.gov/pubmed/33339827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20159-3
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