Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ

Factor-dependent transcription termination mechanisms are poorly understood. We determined a series of cryo-electron microscopy structures portraying the hexameric ATPase ρ on path to terminating NusA/NusG-modified elongation complexes. An open ρ ring contacts NusA, NusG, and multiple regions of RNA...

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Publicado en:Science
Main Authors: Said, Nelly, Hilal, Tarek, Sunday, Nicholas D., Khatri, Ajay, Bürger, Jörg, Mielke, Thorsten, Belogurov, Georgiy A., Loll, Bernhard, Sen, Ranjan, Artsimovitch, Irina, Wahl, Markus C.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864586/
https://ncbi.nlm.nih.gov/pubmed/33243850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd1673
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