Blinded RT-QuIC Analysis of α-Synuclein Biomarker in Skin Tissue from Parkinson’s Disease Patients

BACKGROUND: An unmet clinical need in PD is to identify biomarkers for diagnosis, preferably in peripherally accessible tissues such as skin. Immunohistochemical studies have detected pathological α-synuclein in skin biopsies from PD patients albeit sensitivity needs to be improved. OBJECTIVE: Our s...

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Опубликовано в: :Mov Disord
Главные авторы: Manne, Sireesha, Kondru, Naveen, Jin, Huajun, Serrano, Geidy E., Anantharam, Vellareddy, Kanthasamy, Arthi, Adler, Charles H., Beach, Thomas G., Kanthasamy, Anumantha G.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749035/
https://ncbi.nlm.nih.gov/pubmed/32960470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28242
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