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Ultrasensitive Detection of Aggregated α-Synuclein in Glial Cells, Human Cerebrospinal Fluid, and Brain Tissue Using the RT-QuIC Assay: New High-throughput Neuroimmune Biomarker Assay for Parkinsonian Disorders
Adult-onset neurodegenerative disorders, like Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), that share the accumulation of aggregated α-synuclein (αSyn(agg)) as their hallmark molecular pathology are collectively known as α-synucleinopathies. Diagnosing α-synucleinopathies requires t...
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| Publicado no: | J Neuroimmune Pharmacol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6669119/ https://ncbi.nlm.nih.gov/pubmed/30706414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-019-09835-4 |
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