Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo.

Dysregulated neutrophil (PMN) transmigration across epithelial surfaces (TEpM) significantly contributes to chronic inflammatory diseases, yet mechanisms defining this process remain poorly understood. In the intestine, uncontrolled PMN TEpM is a hallmark of disease flares in ulcerative colitis. Pre...

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Bibliografiset tiedot
Julkaisussa:Mucosal Immunol
Päätekijät: Azcutia, Veronica, Kelm, Matthias, Luissint, Anny-Claude, Boerner, Kevin, Flemming, Sven, Quiros, Miguel, Newton, Gail, Nusrat, Asma, Luscinskas, Francis W., Parkos, Charles A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749029/
https://ncbi.nlm.nih.gov/pubmed/32561828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-0316-4
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