Astrocytic Sonic Hedgehog Alleviates Intracerebral Hemorrhagic Brain Injury via Modulation of Blood-Brain Barrier Integrity

Background: Intracerebral hemorrhage (ICH) is a fatal subtype of stroke that lacks effective therapy. Blood-brain barrier (BBB) damage is a hallmark of ICH-induced brain injury that leads to edema formation, leukocytes infiltration, influx of blood components into the perihematomal (PHE) region, and...

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Pubblicato in:Front Cell Neurosci
Autori principali: Xing, Gebeili, Zhao, Tianman, Zhang, Xiyue, Li, He, Li, Xiuping, Cui, Pan, Li, Minshu, Li, Daojing, Zhang, Nan, Jiang, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cellular Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747855/
https://ncbi.nlm.nih.gov/pubmed/33343302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.575690
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