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mTOR inhibition impairs extinction memory reconsolidation
Fear-motivated avoidance extinction memory is prone to hippocampal brain-derived neurotrophic factor (BDNF)-dependent reconsolidation upon recall. Here, we show that extinction memory recall activates mammalian target of rapamycin (mTOR) in dorsal CA1, and that post-recall inhibition of this kinase...
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| Pubblicato in: | Learn Mem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7747651/ https://ncbi.nlm.nih.gov/pubmed/33323495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.052068.120 |
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