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Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion

There are currently no pharmacological approaches in fracture healing designed to therapeutically stimulate endochondral ossification. In this study, we test nerve growth factor (NGF) as an understudied therapeutic for fracture repair. We first characterized endogenous expression of Ngf and its rece...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Rivera, Kevin O., Russo, Fabrizio, Boileau, Ryan M., Tomlinson, Ryan E., Miclau, Theodore, Marcucio, Ralph S., Desai, Tejal A., Bahney, Chelsea S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747641/
https://ncbi.nlm.nih.gov/pubmed/33335129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78983-y
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