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Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion

There are currently no pharmacological approaches in fracture healing designed to therapeutically stimulate endochondral ossification. In this study, we test nerve growth factor (NGF) as an understudied therapeutic for fracture repair. We first characterized endogenous expression of Ngf and its rece...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Rivera, Kevin O., Russo, Fabrizio, Boileau, Ryan M., Tomlinson, Ryan E., Miclau, Theodore, Marcucio, Ralph S., Desai, Tejal A., Bahney, Chelsea S.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747641/
https://ncbi.nlm.nih.gov/pubmed/33335129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78983-y
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