Targeting the autosomal Ceratitis capitata transformer gene using Cas9 or dCas9 to masculinize XX individuals without inducing mutations

BACKGROUND: Females of the Mediterranean fruit fly Ceratitis capitata (Medfly) are major agricultural pests, as they lay eggs into the fruit crops of hundreds of plant species. In Medfly, female sex determination is based on the activation of Cctransformer (Cctra). A maternal contribution of Cctra i...

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Bibliografiske detaljer
Udgivet i:BMC Genet
Main Authors: Primo, Pasquale, Meccariello, Angela, Inghilterra, Maria Grazia, Gravina, Andrea, Del Corsano, Giuseppe, Volpe, Gennaro, Sollazzo, Germano, Aceto, Serena, Robinson, Mark D., Salvemini, Marco, Saccone, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747381/
https://ncbi.nlm.nih.gov/pubmed/33339496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-00941-4
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