Targeting the autosomal Ceratitis capitata transformer gene using Cas9 or dCas9 to masculinize XX individuals without inducing mutations

BACKGROUND: Females of the Mediterranean fruit fly Ceratitis capitata (Medfly) are major agricultural pests, as they lay eggs into the fruit crops of hundreds of plant species. In Medfly, female sex determination is based on the activation of Cctransformer (Cctra). A maternal contribution of Cctra i...

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Vydáno v:BMC Genet
Hlavní autoři: Primo, Pasquale, Meccariello, Angela, Inghilterra, Maria Grazia, Gravina, Andrea, Del Corsano, Giuseppe, Volpe, Gennaro, Sollazzo, Germano, Aceto, Serena, Robinson, Mark D., Salvemini, Marco, Saccone, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747381/
https://ncbi.nlm.nih.gov/pubmed/33339496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-00941-4
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