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Toll-like receptor signalling in B cells during systemic lupus erythematosus

B lymphocytes have a central role in autoimmune diseases, which are often defined by specific autoantibody patterns and feature a loss of B cell tolerance. A prototypic disease associated with B cell hyperactivity is systemic lupus erythematosus (SLE). In patients with SLE, the loss of B cell tolera...

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Библиографические подробности
Опубликовано в: :Nat Rev Rheumatol
Главные авторы: Fillatreau, Simon, Manfroi, Benoît, Dörner, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747191/
https://ncbi.nlm.nih.gov/pubmed/33339987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41584-020-00544-4
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