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Toll-like Receptors in Systemic Lupus Erythematosus Prospects for Therapeutic Intervention
Recent experimental and clinical studies have placed new emphasis on the role of the innate immune system in SLE. Nucleic acid-containing immune complexes activate the innate response by engaging specific Toll-like receptors (TLRs) and promote the generation of autoantibodies. Pharmacologic modulati...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654252/ https://ncbi.nlm.nih.gov/pubmed/18722558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autrev.2008.07.046 |
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