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A Highly Expressing, Soluble, and Stable Plant-Made IgG Fusion Vaccine Strategy Enhances Antigen Immunogenicity in Mice Without Adjuvant

Therapeutics based on fusing a protein of interest to the IgG Fc domain have been enormously successful, though fewer studies have investigated the vaccine potential of IgG fusions. In this study, we systematically compared the key properties of seven different plant-made human IgG1 fusion vaccine c...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Diamos, Andrew G., Pardhe, Mary D., Sun, Haiyan, Hunter, Joseph G. L., Kilbourne, Jacquelyn, Chen, Qiang, Mason, Hugh S.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746858/
https://ncbi.nlm.nih.gov/pubmed/33343565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.576012
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