Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL

Growth and differentiation factor 15 (GDF-15) has been studied as an important hallmark of cancer. However, the receptor of GDF-15 in pancreatic cancer cell remains unclear. Here, we investigated its biological effects in pancreatic ductal adenocarcinoma (PDAC). We found that aberrant GDF-15 express...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging (Albany NY)
Prif Awduron: Zhao, Zhiping, Zhang, Junfeng, Yin, Liangyu, Yang, Jiali, Zheng, Yao, Zhang, Mengjie, Ni, Bing, Wang, Huaizhi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals 2020
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746332/
https://ncbi.nlm.nih.gov/pubmed/33201838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103830
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