Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL

Growth and differentiation factor 15 (GDF-15) has been studied as an important hallmark of cancer. However, the receptor of GDF-15 in pancreatic cancer cell remains unclear. Here, we investigated its biological effects in pancreatic ductal adenocarcinoma (PDAC). We found that aberrant GDF-15 express...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhao, Zhiping, Zhang, Junfeng, Yin, Liangyu, Yang, Jiali, Zheng, Yao, Zhang, Mengjie, Ni, Bing, Wang, Huaizhi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746332/
https://ncbi.nlm.nih.gov/pubmed/33201838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103830
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