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A pipeline for precise and efficient genome editing by sgRNA-Cas9 RNPs in Drosophila
Genome editing via homology-directed repair (HDR) has made possible precise and deliberate modifications to gene sequences. CRISPR/Cas9-mediated HDR is the simplest means to carry this out. However, technical challenges remain to improve efficiency and broaden applicability to any genetic background...
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| Publicat a: | Fly (Austin) |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7746241/ https://ncbi.nlm.nih.gov/pubmed/33016195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336934.2020.1832416 |
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