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Suprachoroidally Delivered DNA Nanoparticles Transfect Retina and Retinal Pigment Epithelium/Choroid in Rabbits
PURPOSE: This study evaluated ocular tolerability and transfectability of nonviral DNA nanoparticles (DNPs) after microneedle-based suprachoroidal (SC) administration, in comparison to subretinal (SR) administration. METHODS: The DNPs consisted of a single copy of plasmid DNA with a polyubiquitin C/...
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| Publicat a: | Transl Vis Sci Technol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Association for Research in Vision and Ophthalmology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745627/ https://ncbi.nlm.nih.gov/pubmed/33364076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.9.13.21 |
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