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Inhibition of ornithine decarboxylase restores hypoxic pulmonary vasoconstriction in endotoxemic mice
Endotoxemia impairs hypoxic pulmonary vasoconstriction which leads to systemic hypoxemia. This derogation is attributable to increased activity of nitric oxide synthase 2 and arginase metabolism. Gene expression analysis has shown increased expression of ornithine decarboxylase in lungs of endotoxem...
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| Publicat a: | Pulm Circ |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SAGE Publications
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745575/ https://ncbi.nlm.nih.gov/pubmed/33403098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020915831 |
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