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Inhibition of ornithine decarboxylase restores hypoxic pulmonary vasoconstriction in endotoxemic mice
Endotoxemia impairs hypoxic pulmonary vasoconstriction which leads to systemic hypoxemia. This derogation is attributable to increased activity of nitric oxide synthase 2 and arginase metabolism. Gene expression analysis has shown increased expression of ornithine decarboxylase in lungs of endotoxem...
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| Publicado no: | Pulm Circ |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745575/ https://ncbi.nlm.nih.gov/pubmed/33403098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020915831 |
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