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In Silico ADME, Metabolism Prediction and Hydrolysis Study of Melatonin Derivatives
Melatonin (MLT) is a well-known pineal hormone possessed with remarkable biological activities. However, its low oral bioavailability and high first-pass metabolism rate are important pharmacokinetics problems. Therefore, 5 MLT derivatives (1-5) were designed and synthesised in our group to solve th...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Int J Tryptophan Res |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
SAGE Publications
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745548/ https://ncbi.nlm.nih.gov/pubmed/33402831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1178646920978245 |
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