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In Silico ADME, Metabolism Prediction and Hydrolysis Study of Melatonin Derivatives
Melatonin (MLT) is a well-known pineal hormone possessed with remarkable biological activities. However, its low oral bioavailability and high first-pass metabolism rate are important pharmacokinetics problems. Therefore, 5 MLT derivatives (1-5) were designed and synthesised in our group to solve th...
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| Publicado no: | Int J Tryptophan Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745548/ https://ncbi.nlm.nih.gov/pubmed/33402831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1178646920978245 |
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