Hydrogen sulfide releasing molecule MZe786 inhibits soluble Flt-1 and prevents preeclampsia in a refined RUPP mouse model

An imbalance in angiogenic growth factors and poor utero-placental perfusion are strongly associated with preeclampsia. The reduced utero-placental perfusion (RUPP) model that mimics insufficient placental perfusion is used to study preeclampsia. The aim of this study was to develop a refined RUPP m...

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Veröffentlicht in:Redox Biol
Hauptverfasser: Saif, Jaimy, Ahmad, Shakil, Rezai, Homira, Litvinova, Karina, Sparatore, Anna, Alzahrani, Faisal A., Wang, Keqing, Ahmed, Asif
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744945/
https://ncbi.nlm.nih.gov/pubmed/33321463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101814
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